Explore our seminal paper and other research work featuring STRIDE.
sSTRIDE as a technology platform for the detection and measurement of DNA breaks in various DNA repair pathways (DDR Inhibitors Summit 2024)
Maja Białecka, Karolina Uznańska, Olga Wójcikowska, Kamil Solarczyk, et al.
Detection of DNA damage using STRIDE as a new PD biomarker in liquid biopsies and FFPE tissue sections
Kamil Solarczyk, Agnieszka Waligórska, Małgorzata Szczygieł, Paul Waring, Gemma Jones, et al.
LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair
Jianli Zhou, Drew Sturtevant, Cassie Love, Aditya Kulkarni, Kishor Bhatia, et al.
Development and validation of a novel sSTRIDE-MMR functional assay to study the efficiency of MMR inhibitors (AACR 2023)
Maja Białecka, Kamil Solarczyk, Karolina Uznańska, Olga Wójcikowska, et al.
Novel functional dSTRIDE-HR assays to report on the status of homologous recombination repair in cancer cells (AACR 2023)
Kamil Solarczyk, Agnieszka Waligórska, Karolina Uznańska, Zsombor Prucsi, et al.
Let’s not take DNA breaks for granted. The importance of direct detection of DNA breaks for the successful development of DDR inhibitors
Magdalena M Kordon and Kamil Solarczyk
STRIDE—a fluorescence method for direct, specific in situ detection of individual single- or double-strand DNA breaks in fixed cells
Magdalena M Kordon, Mirosław Zarębski, Kamil Solarczyk, Hanhui Ma, Thoru Pederson, Jurek W Dobrucki
Ubiquitinated PCNA drives USP1 synthetic lethality in cancer
Antoine Simoneau, Justin Engel, Madhavi Bandi, Katherine Lazarides, Shangtao Liu, et al.
Breakage of CRISPR/Cas9-Induced Chromosome Bridges in Mitotic Cells
Marina Rodriguez-Muñoz, Martina Serrat, David Soler, Anna Genescà and Teresa Anglada
PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity
Joseph Gozgit, Melissa Vasbinder, Ryan Abo, Kaiko Kunii, Kristy Kuplast-Barr, et al.